Перегляд за автором "Kovalevska, L.M."

Результати 1-8 з 8

CD150 and CD180 are involved in regulation of transcription factors expression in chronic lymphocytic leukemia cells

Gordiienko, I.M.; Shlapatska, L.M.; Kholodniuk, V.M.; Kovalevska, L.M.; Ivanivskaya, T.S.; Sidorenko, S.P. (Experimental Oncology, 2017)

Background: Sequential stages of B-cell development is stringently coordinated by transcription factors (TFs) network that include B-lineage commitment TFs (Ikaros, Runx1/Cbfb, E2A, and FOXO1), B-lineage maintenance TFs ...
Differential expression of CD150/SLAMF1 in normal and malignant b cells on the different stages of maturation

Gordiienko, I.M.; Shlapatska, L.M.; Kovalevska, L.M.; Sidorenko, S.P. (Experimental Oncology, 2016)

Background: Within B-cell lineage cell surface receptor CD150/SLAMF1 is broadly expressed starting from pre-B cells with upregulation toward plasma cells. However, expression of CD150 is rather limited on the surface of ...
Differential expression of PKD1 and PKD2 in gastric cancer and analysis of PKD1 and PKD2 function in the model system

Shabelnik, M.Yu.; Kovalevska, L.M.; Yurchenko, M.Y.; Shlapatska, L.M.; Rzepetsky, Yu.; Sidorenko, S.P. (Experimental Oncology, 2011)

Aim: To study the differential expression of PKD1 and PKD2 in primary gastric cancer samples and to examine the role of PKD1 and PKD2 protein kinases in regulation of gastric tumor cell biology in the model system. Methods: ...
Immunohistochemical studies of protein kinase D (PKD) 2 expression in malignant human lymph

Shlapatska, L.M.; Sidorenko, S.P.; Yurchenko, O.V.; Berdova, G.G.; Mikhalap, S.V.; Lint J. Van; Kovalevska, L.M. (Experimental Oncology, 2006)

Aim: To study the PKD2 expression, autophosphorylation and localization in reactive lymph nodes and tumors of lymphoid tissues. Materials and Methods: Specific antibodies, which recognize PKD1/2 or PKD2 and autophosphorylated ...
Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. I. Cell surface phenotype and functional studies

Shlapatska, L.M.; Kovalevska, L.M.; Gordiienko, I.M.; Sidorenko, S.P. (Experimental Oncology, 2014)

Background: Mutations in SH2D1A/DSHP/SAP gene are responsible for the onset of X-linked lymphoproliferative disease type 1 (XLP1) that have increased risk for B-cell lymphoma development. In XLP1 patients SAP deficient NK, ...
Intrinsic defect in B-lymphoblastoid cell lines from patients with X-linked lymphoproliferative disease type 1. II. Receptor-mediated Akt/PKB and ERK1/2 activation and transcription factors expression profile

Shlapatska, L.M.; Kovalevska, L.M.; Gordiienko, I.M.; Sidorenko, S.P. (Experimental Oncology, 2014)

Background: X-linked lymphoproliferative disease type 1 (XLP1) belongs to genetically determined primary immunodeficiency syndromes with mutations in SH2D1A/DSHP/SAP gene. The dramatic increase of the risk of B-cell lymphoma ...
TGF-β1 expression by glioma C6 cells in vitro

Liubich, L.D.; Kovalevska, L.M.; Lisyany, M.I.; Semenova, V.M.; Malysheva, T.A.; Stayno, L.P.; Vaslovych, V.V. (Experimental Oncology, 2017)

The aim of the work was to study the impact of fetal rat brain cell supernatant (FRBCS) on the expression of transforming growth factor β1 (TGF-β1) and p53 in C6 cells of rat glioma in vitro. Materials and Methods: FRBCS ...
The STAT5 transcription factor in B-cells of patients with chronic lymphocytic leukemia

Matvieieva, A.S.; Kovalevska, L.M.; Ivanivska, T.S.; Klein, E.; Kashuba, E.V. (Вiopolymers and Cell, 2019)

Aim. To find out the cause of inhibition of the IL2-STAT5 signaling pathway in chronic lymphocytic leukemia (CLL) cells. Methods.CLL cells were isolated from peripheral blood, using gradient centrifugation on a ficoll-verografin ...

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Перегляд за автором "Kovalevska, L.M."

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Перегляд за автором "Kovalevska, L.M."

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